Temporal and Spatial Changes in Collateral Formation and Function During Chronic Myocardial Ischemia
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چکیده
منابع مشابه
simulation and experimental studies for prediction mineral scale formation in oil field during mixing of injection and formation water
abstract: mineral scaling in oil and gas production equipment is one of the most important problem that occurs while water injection and it has been recognized to be a major operational problem. the incompatibility between injected and formation waters may result in inorganic scale precipitation in the equipment and reservoir and then reduction of oil production rate and water injection rate. ...
Adenoviral PR39 improves blood flow and myocardial function in a pig model of chronic myocardial ischemia by enhancing collateral formation.
Angiogenic therapy with individual growth factors or "master switch" genes is being evaluated for treatment of advanced coronary artery disease. In this study, we investigated the efficacy and mechanism of PR39, a gene capable of activating VEGF and fibroblast growth factor (FGF)-2-dependent pathways. PR39 enhances hypoxia-inducible factor-1alpha (HIF-1alpha)-dependent gene expression by select...
متن کاملCALL FOR PAPERS Angiogenesis in Health and Disease Adenoviral PR39 improves blood flow and myocardial function in a pig model of chronic myocardial ischemia by enhancing collateral formation
Mark J. Post, Kaori Sato, Masahiro Murakami, Jialin Bao, Daniela Tirziu, Justin D. Pearlman, and Michael Simons Angiogenesis Research Center and Section of Cardiology, Dartmouth Medical School, Lebanon, New Hampshire; Beth Israel Deaconess Medical Center, Boston, Massachusetts; and Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Net...
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In the anesthetized open-chest dog the ischemic area produced by coronary occlusion is surrounded by an area of nonischemic contractile dysfunction, identified as the functional border zone. To establish whether a similar functional border zone exists in the conscious animal during acute regional ischemia and to determine its spatial dimensions and temporal changes, we performed simultaneous tw...
متن کاملST changes and temporal relation to the J point during heart rate increase and myocardial ischemia.
There is no concensus concerning where in the ST segment to measure. We studied the relation between different J point intervals to ST results during tachycardia and ischemia. Symptomatic (anesthetized) patients with coronary artery disease were paced at ascending incremental levels until they became ischemic. ST vector magnitude and ST vector change from baseline (STC-VM) as well as the sum of...
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ژورنال
عنوان ژورنال: Journal of the American College of Surgeons
سال: 2010
ISSN: 1072-7515
DOI: 10.1016/j.jamcollsurg.2010.06.009